The GLP-1 Activator
You already have GLP-1. Activate it.

How to Take Calocurb® CLINICAL
Clinical study results for Calocurb® CLINICAL include:

Hunger and Cravings
Eating healthy and losing weight—or keeping it off—can be difficult when hunger and cravings seem to overpower your best intentions. Even with a balanced diet and active lifestyle, your body’s natural appetite signals can make portion control or diet changes challenging. Calocurb® CLINICAL is designed to support healthy weight management by working with your body’s own satiety pathways to reduce hunger and curb cravings.
How Calocurb® CLINICAL Works
Targeted Delivery
Calocurb® CLINICAL is designed to release in the small intestine where it activates bitter taste receptors in the gut.
Gut Peptide Activation
As bitter taste receptors are activated, they enhance the body's production of gut peptides—like GLP-1—that suppress hunger and cravings.
Fast Results That Last
Concentrated Calocurb® CLINICAL starts working after one hour with results that last up to six hours.

Calocurb® CLINICAL Research
Calocurb® CLINICAL was administered at hours 16 and 20 of a 24-hour water fast. Within one hour, participants reported significant reductions in hunger and cravings. Compared to placebo, Calocurb® CLINICAL completely suppressed the normal elevation of hunger and cravings. Overall, the participants had a 30% reduction in hunger and a 40% reduction in cravings.1


New 24-Week Study
See the recently published research on bitter hops and its effects on weight, body fat, visceral fat and muscle mass.
Calocurb® CLINICAL SUPPORTS WEIGHT LOSS WHILE PERSERVING MUSCLE MASS


Calocurb® CLINICAL Q&A
What should I expect when taking Calocurb® CLINICAL?
Most people notice a reduction in appetite and food cravings after 1 hour of taking Calocurb® CLINICAL. The effects can last for 4–6 hours.
During the first few days (about 72 hours), some people may experience a temporary “flushing” effect, such as more frequent bowel movements or mild diarrhea. This is usually short-lived and improves as your body adjusts. If you have ongoing digestive issues, these effects may last a bit longer.
A small number of people may be more sensitive to the product. If symptoms persist or are bothersome, it’s a good idea to speak with your healthcare provider.
Who should not take Calocurb® CLINICAL?
Calocurb® CLINICAL is not recommended for people with inflammatory bowel disease (IBD), such as Crohn’s disease or ulcerative colitis.
If you have ongoing digestive issues, you may be more likely to experience side effects. In those cases, it’s a good idea to speak with your healthcare provider, as you may need adjustments or additional support to use the product comfortably.
I’m having trouble remembering when to take my second dose—what should I do?
To work properly, Calocurb® CLINICAL needs to be taken on an empty stomach. If you take it too close to a meal, it may not work as well.
A helpful tip is to set a timer after you eat. Most people’s stomachs are empty about 3–4 hours after a meal. For example, if you want to take it before lunch, you can set a reminder after breakfast. Then take your dose and wait about 1 hour before eating.
Keeping a routine or setting phone reminders can make it much easier to stay on track.
What does it mean if I have loose stools from Calocurb® CLINICAL?
Some people may experience loose stools or diarrhea when first starting Calocurb® CLINICAL as the digestive system adjusts. In most cases, these symptoms are temporary and improve within the first 72 hours.
If diarrhea lasts longer than 72 hours, contact your healthcare provider for further guidance.
What does it mean if I feel heartburn or nausea after taking Calocurb® CLINICAL?
This can happen if the capsule opens in your stomach instead of further down in your digestive system. It’s more likely if you take it too close to a meal, don’t drink enough water, or your stomach hasn’t fully emptied yet.
To help prevent this, try taking Calocurb® CLINICAL on an empty stomach, about 2 hours before eating, with a large glass of water (12–16 oz).
If symptoms continue, check with your healthcare provider.
Directions for Use
CLINICAL STARTER PACK
This pack onboards your body to the increased activation of natural satiety hormones.


ID# 721060
Contains: 10 x 125 mg
capsules and 50 x 250 mg
capsules
Day 1-2: Take one 125 mg capsule one hour before a meal.
Day 3-4: Take one 125 mg capsule, twice daily, one to two hours before a meal.
Day 5: Take two 125 mg capsules, twice daily, one to two hours before a meal.
Day 6+: Take one 250 mg capsule, twice daily, one to two hours before a meal.
Always take on an empty stomach with a large glass of water.
CLINICAL Maintenance PACK
Using the Maintenance Pack, continue on a dose of Calocurb® CLINICAL 250 mg twice daily.


ID# 722060
Contains: 160 x 250 mg capsules
Take one 250 mg capsule, twice daily, one to two hours before a meal.
Always take on an empty stomach with with a large glass of water.